Migraine Cocktail – How it Helps Relieve Headache

With more than 35 million Americans reported to suffer from migraine, which is more than 12% of the American population, this is definitely one of the most common health issues people confront with in the modern days.

Migraine can cause flashes of lights, nausea, blind spot and severe pain that last for hours.

This type of headache is most common in women, but men suffer from it too.

What is a migraine really?

Well, it is a recurrent painful and severe headache that usually affects one side of the head and is accompanied by other symptoms such as:

  • Nausea
  • Vision distortion
  • Vomiting
  • Pain behind one eye or ear or increased sensitivity to light or sound.

While these symptoms are really bad on their own, when combined they’re even worse.

But medicine found an effective treatment for all migraines, even the worst ones. The best remedy for migraines is called migraine cocktail.

As the name suggests, it is as combination of three drugs:

  • Prochlorperazine
  • Indomethacin
  • Caffeine.

One of the most important aspects is using the right dosage, but a doctor will know exactly what to prescribe.

The migraine cocktail is made up of: 10mg prochlorperazine, 25mg indomethacin and 50mg caffeine.

While caffeine is an over-the-counter medication, the other two are prescription drugs that you will not be able to buy without a medical prescription.


For the migraine cocktail to do the trick and release you from the excruciating pain of a severe and recurring headache, the drugs have to be taken in a specific way.

When you get the first headache symptoms, take one of each drugs and take them together. The migraine cocktail has to be taken every eight hours, but not more than three times a day.

Since you’re taking this many pills and they’re quite strong too, take them with food, because otherwise you might switch from headache to stomach ache and other digestive issues.

The migraine cocktail is not only effective but also cost saving, compared to other migraine drugs.

But how do these three drugs work?

Caffeine is known for its role in reducing inflammation; it can bring relief but also boost other drugs’ effects. Therefore, it helps the migraine cocktail be as effective as it is.

Prochlorperazine is a medication known for its role in treating severe nausea and vomiting, two symptoms very common in migraines.

Indometacin, the third ingredient of the migraine cocktail is a non-steroidal anti-inflammatory drug. It is commonly used to reduce symptoms such as pain, fever and stiffness. The way it works is by inhibiting the production of prostaglandins that actually causes these symptoms in the first place.

This drug actually has many other clinical indications; besides headache and migraine, it also helps in kidney stones, osteoarthritis, pericarditis and many more.

As you can see, all these three are very effective and useful drugs that have the role of improving the overall health and treating a wide range of affections.

Combined however, the three drugs manage to treat migraines and all of its symptoms – severe headache and its side effects.

If you’re one of the people suffering from migraines and have tried all kinds of medication before but without seeing an actual health improvement and pain relief, you should consult your doctor and discuss the possibility of trying a migraine cocktail.

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Dr. Sachin

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